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February 2008

The Electronic Sarcoma Update Newsletter, Vol. 5, No. 1

Each of the words or phrases that are underlined and in a bold blue type in ESUN are hyperlinks to websites, documents or articles. Each title in the table of contents, In This Issue, is a link to the specific article. All the external hyperlinks appearing in ESUN were valid when the issue of ESUN was published. If you find any broken links, please send us a note about them. The document hyperlinks typically open PDF documents, so you should have the Adobe Acrobat Reader installed on your system in order to read them.

 

In This Issue

Feature Articles

Three Research Grants Announced

Editorial by Bruce Shriver, PhD

CTOS Op Ed: Of Mice and Men

Brian Rubin, M.D. tells why we need to embrace mouse models of human sarcoma.

CTOS Op Ed: Questions, Comments and Counterpoints

Robert Maki, M.D. responds to a letter from Archie Bleyer. M.D.

Identification and Characterization of the Ewing’s Sarcoma Stem Cell

David Loeb, M.D., Ph.D. describes his research in Ewing's sarcoma stem cells.

Novel Targets to Treat Osteosarcoma Lung Metastases

Nadezhda Koshkina, Ph.D. and Seth Corey, M.D. describe their research in osteosarcoma metastases.

Small Molecules That Can Inhibit EWS-FLI1 May Represent Novel and Specific Therapy for ESFT Patients

Jeffrey Toretsky, M.D. describes his research towards identification of small molecule protein-protein interaction inhibitors.

From A Nurse's Perspective: Clinical Trials

Denise Reinke, RN, NP, Kelly Scheu, MS, NP, and Marcia E. Baker, DO, FACOI discuss clinical trials. Fill out and send in the questionnaire in this article.

An Update on the Sarcoma Alliance

Arthur Beckert reviews the new website and some of the programs of the Sarcoma Alliance.

A Review of the October 2007 Meeting of the International Sarcoma Patient Advocate Network (iSPAN)

Matt Alsante, Arthur Beckert, and Melissa Hill review what took place at the most recent iSPAN meeting.

A Partial Index to Articles that have Appeared in ESUN

We give an updated partial index to ESUN articles.

Regular Columns

Clinical Trial News 

Tom Swartz describes various clinical trials
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Currently Accepting Eligible Patients (not previously published in ESUN)

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Currently Accepting Eligible Patients (previously published in ESUN and additional information is now available)

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Not Yet Recruiting Patients (not previously published in ESUN)

Odds & Ends

Pointers to resources and abstracts of interesting articles. In this issue:
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The Amschwand Sarcoma Cancer Foundation Expands its Corporate Apartment Program

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Positron Emission Tomography Superior To Standard Evaluation Tools In Measuring Treatment Response In Sarcoma Patients

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Soft-Tissue Sarcoma Outcomes Vary Widely by Race, Ethnicity

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American Psychosocial Oncology Society Referral Helpline

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A Gift from the Miles Alpern Levin Philanthropic Fund and the Joanna McAfee Childhood Cancer Foundation

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The Broad Institute

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Cancer Vaccine Consortium and Cancer Vaccine Collaborative Unite under the Cancer Research Institute

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See-through fish is created to give a clearer idea of how cancer spreads

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Parent distress in childhood cancer: A comparative evaluation of posttraumatic stress symptoms, depression and anxiety

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Understanding high-quality cancer care - A summary of expert perspectives

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The Sarcoma Foundation of America's Patient registry

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Monitoring for Cardiovascular Disease in Survivors of Childhood Cancer: Report From the Cardiovascular Disease Task Force of the Children's Oncology Group

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At Press Time

Research Corner

Abstracts of recent sarcoma-related research articles. In this issue:
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The effect of an unplanned excision of a soft-tissue sarcoma on prognosis

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Radiological and pathological diagnosis of paediatric bone tumours and tumour-like lesions

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Radiological features of synovial cell sarcoma

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Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas

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Induction of Cancer Metastasis by Cyclophosphamide Pretreatment of Host Mice: An Opposite Effect of Chemotherapy

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Prognostic Implications of Glucose Transporter Protein-1 (Glut-1) Overexpression in Bone and Soft-Tissue Sarcomas

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Phase I Trial of the Novel Mammalian Target of Rapamycin Inhibitor Deforolimus (AP23573; MK-8669) Administered Intravenously Daily for 5 Days Every 2 Weeks to Patients With Advanced Malignancies

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Clinical pharmacology of cancer therapies in older adults

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Myeloablative therapy with autologous stem cell rescue for patients with Ewing sarcoma

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Multimodality treatment of osteosarcoma: Radiation in a high-risk cohort

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At Press Time

Stories of Courage and Hope

Tom Swartz abstracts several inspiring stories we have recently encountered about patients or caregivers that tell of the strength that some are blessed with in dealing with sarcoma. In this issue:
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Doctorate helps complete cancer victim's journey

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Cancer never stood a chance against patient's zest for life

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Unborn twins 'kicked out cancer'

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You obviously have to fight it

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Cancer Won't End Dreams

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Better Days Ahead

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Chasing dreams in the face of cancer

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A Boy and His Dog

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Fighting cancer at 13

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Silvertips' Irving is a survivor

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Spirit and Support – Stronger than Every Diagnosis

Our Initiatives

Brief descriptions of some of the Liddy Shriver Sarcoma Initiative projects are presented. In this issue:

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First Annual James Stulce Memorial Dinner Dance and Silent Auction

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"Sarcoma Wins Big" in the Facebook Causes Giving Challenge

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Team Sarcoma Event planning is underway to be part of the 2008 Team Sarcoma Initiative during July 12-20, 2008

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The Faces of Sarcoma Project

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The "Sarcoma Knows No Borders" Bracelet 

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Music CD, The Circle, Benefits Sarcoma Research

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Clinical trial abstracts now exceed 250

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Guest Book

General Information

Disclaimer

Medical Editorial Board and Editorial Staff

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Send us a note containing your e-mail address if you would like to receive a note when the next issue of ESUN is published.

Topics and Feedback

Please send us your recommendations for topics that you would like to see covered in ESUN as well as any other comments or feedback that can be useful to us. We also welcome contributions of essays and articles that are relevant to ESUN and its intended audience

 

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